In the year 2825, with a new variant of Plague 22 rampant in New York, the citizens of the New Commonwealth have adapted to the crisis through a combination of advanced technology, community resilience, and innovative public health measures. Here are some ways in which people survive:

1. Advanced Medical Technology: The healthcare system has embraced cutting-edge biotechnology. Nanobots in the bloodstream detect and combat the virus at the cellular level, providing targeted treatment and boosting the immune system. Personalized medicine, based on individual genetic profiles, allows for tailored vaccines and treatments.

2. Quarantine Zones: Areas of New York are designated as quarantine zones, where those infected or exposed are isolated from the general population. These zones are equipped with biohazard containment facilities and staffed by trained medical personnel. Drones deliver supplies, food, and medication to these zones to minimize contact between infected and healthy individuals.

3. Virtual Reality (VR) Communities: With many people confined to their homes, VR technology has become a vital social tool. Citizens can enter virtual communities, attend events, and maintain social connections while minimizing the risk of infection. This helps combat the mental strain of isolation and allows for a sense of normalcy.

4. Community Networks: Neighborhood support groups have formed to help those in need, providing food, medication, and other essentials. Using secure communication apps, volunteers coordinate deliveries and health check-ins, fostering a strong sense of community.

5. Enhanced Surveillance and Contact Tracing: Wearable devices equipped with AI alongside advanced tracking apps help monitor exposure risks in real-time. These systems facilitate quick notification of potential exposure, enabling rapid response and containment of new infections.

6. Psycho-social Support: Mental health resources are readily available, including teletherapy, mindfulness apps, and support groups. Recognizing the psychological toll of the outbreak is crucial, and initiatives are in place to help individuals cope with anxiety and stress.

7. Alternative Livelihoods: Many businesses have pivoted to online platforms, fostering remote work and virtual commerce. Gig economies and tech-based services thrive, allowing citizens to sustain their livelihoods while adhering to public health guidelines.

8. Public Engagement and Education: Continuous public health campaigns utilize holographic displays and interactive digital media to educate citizens about hygiene, vaccination, and safe practices to curb the spread of the virus.

9. Innovative Agriculture: With supply chains disrupted, urban vertical farms and hydroponic systems have become essential. These farms improve food security and reduce dependency on external suppliers, allowing residents to access fresh produce more easily.

10. Global Collaboration: Despite the pandemic, nations engage in collaborative research to share data and rapidly develop treatments and vaccines. The global community works together in solidarity, recognizing that the fight against Plague 22 is a shared responsibility.

Through these strategies, the people of New Commonwealth not only survive but begin to redefine their ways of living in a world shaped by the realities of pandemics and technological advances.